Optimizing the Use of Prophylaxis in Patients With Severe Haemophilia A
Status:
Completed
Trial end date:
2021-04-09
Target enrollment:
Participant gender:
Summary
MyPKFiT is a web-based application recently developed by Baxalta for the use in patients
treated with Advate. MyPkFit has its basis in Bayesian forecasting, which allows estimation
of individual PK parameters by a sparse sampling schedule, where only 2-3 samples are taken
between 4 and 48 hours post infusion. With myPKFiT, it will, therefore, be possible to define
an individual PK curve for each patient based on just a few sampling points and hence, taking
the bleeding phenotype and the life style into account, potentially adjust the prophylactic
treatment accordingly to optimize cost-effectiveness.