Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy
Status:
Completed
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
This is a pragmatic, open-label, randomised control trial of three oral anti-hypertensive
regimens for women with severe hypertension in pregnancy. Women presenting with severe
hypertension in pregnancy in two hospitals in Nagpur, India will be randomised to one of
three oral regimens: nifedipine, labetalol or methyldopa. This trial will compare the
efficacy, safety and side effects of these three oral regimens for management of hypertension
in pregnant women. The investigators hypothesize that nifedipine treatment of severe
hypertensive parturient women is more effective than treatment with labetalol or methyldopa
in controlling high blood pressure within six hours.
Phase:
Phase 4
Details
Lead Sponsor:
Gynuity Health Projects
Collaborators:
Bill and Melinda Gates Foundation Daga Memorial Women's Hospital, Nagpur, India Government Medical College, Nagpur University of British Columbia