Oral Care Interventions and Ventilator Associated Pneumonia in Critically Ill Children
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
This experimental study aims to verify the influence of the oral hygiene performance with
chlorhexidine digluconate 0.12% in the development of VAP in children. The data collection
begun in April, 2005 during the performance of the masters degree course dissertation
entitled "Clinical study about the effect of the oral hygiene with chlorhexidine digluconate
0.12% in the oropharynx colonization of children in intensive care", being performed in a
PICU of nine beds in a university hospital in the city of São Paulo, after approval of the
Research Ethics Committee of the institution. The study is composed by three types of
variables: Independent variable, dependent variables, and complementary variables. The
categorical variables will be analyzed in accordance with the Person's Chi-Square test of or
Fisher's exact test. The numerics will be submitted to the analysis of variance ANOVA or
Kruskall Wallis. For variables with heterogeneous distribution between the groups, the
multivariate analysis will be applied to the evaluation of the influence in the determination
of the development risk of the dependent variable. The rejection level will be fixed in 0.05
of the nullity hypothesis.
Phase:
Phase 1
Details
Lead Sponsor:
Federal University of São Paulo
Collaborator:
Fundação de Amparo à Pesquisa do Estado de São Paulo