Oral Dexamethasone for the Treatment of Acute Migraine Recurrence in the Pediatric Emergency Department
Status:
Completed
Trial end date:
2017-06-28
Target enrollment:
Participant gender:
Summary
Migraine recurrence is common amongst pediatric patients being discharged from the emergency
department after treatment for migraine. Despite the commonality of migraine recurrence
within the week following discharge, no known effective therapies are available in the
pediatric population, though dexamethasone has been established as efficacious in the adult
migraine population. The proposed study will randomly assign children and adolescents
visiting the emergency department (ED) for migraine to receive either one dose of oral
dexamethasone or oral placebo. Twenty patients will be recruited to this randomized,
double-blind, pilot trial over a 6 month period, and the aim of the study will be to
determine the feasibility and acceptability of the protocol.