Oral Ibuprofen Versus Placebo in Treatment of Patent Ductus Arteriosus (PDA)in Preterm Infants
Status:
Recruiting
Trial end date:
2022-09-01
Target enrollment:
Participant gender:
Summary
The management options of Patent Ductus Arteriosus are still controversial and differ between
centers. Recently, conservative management has been gaining interest as the evidence of
benefit from medical treatment in terms of mortality and morbidity is lacking.
This study will compare oral ibuprofen (the standard treatment) with the conservative
treatment, in terms of ductal closure and morbidity and mortality at discharge in preterm
neonates less than 34 weeks.