Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure
Status:
Completed
Trial end date:
2016-04-06
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if oral iron (Fe) polysaccharide is superior to
oral placebo in improving functional capacity as measured by change in peak VO2 (oxygen
uptake) by CPET (Cardiopulmonary Exercise Testing) , of a broad population of patients with
HFrEF (Heart Failure with Reduced Ejection Fraction) and Fe deficiency at 16 weeks.
Hypothesis: In a broad population of HFrEF patients with Fe deficiency, compared to oral
placebo, therapy with oral Fe polysaccharide will be associated with improvement in
functional capacity at 16 weeks as assessed by CPET.