Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children

• Status: Unknown status
• Trial end date: 2017-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Scabies remains a frequent condition that affects adults and children. The aim of this study is to compare the efficacy and safety of two drug treatments against scabies in children and their close contacts. One group will apply topical permethrin 5% and the other group will receive oral ivermectin.

Both groups will be treated twice, once at inclusion and the second time 10 days later. Both treatment regimens have been used widely and are safe to use.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Bordeaux
• Treatments: Ivermectin; Permethrin

Criteria

Inclusion Criteria:

• Age less than 16 years

• Weight more than 15 kg

• Documented diagnosis of scabies, defined by positive dermoscopic examination.

Exclusion Criteria:

• Previous scabies therapy during the past 4 weeks

• Known allergy to ivermectin or permethrin

• Widespread eczematization or impetiginization

• Liver or renal failure