Overview Oral Methadone in Cardiac Surgery Status: NOT_YET_RECRUITING Trial end date: 2026-08-01 Target enrollment: Participant gender: Summary The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.Phase: PHASE4 Details Lead Sponsor: Mayo ClinicTreatments: Methadone