Oral Misoprostol Before Endometrial Biopsy

• Status: Completed
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Memorial University of Newfoundland
• Treatments: Misoprostol; Pyridoxal; Pyridoxine; Vitamin B 6; Vitamin B Complex; Vitamins

Criteria

Inclusion Criteria:

• women 19 years and older

• planned endometrial biopsy

Exclusion Criteria:

• known hypersensitivity or allery to prostaglandins

• seizure disorder

• liver disease

• known abnormal liver function tests

• pregnancy