Oral Prednisolone Dosing in Children Hospitalized With Asthma
Status:
Completed
Trial end date:
2006-11-01
Target enrollment:
Participant gender:
Summary
This study hopes to determine the appropriate oral steroid dose for treating children
hospitalized with asthma exacerbations. Practice guidelines from different countries
recommend a wide range of doses, and the doses used in actual practice vary widely. There is
no data on what is the most appropriate dose of prednisone (or equivalent) in this situation.
We will be looking at the dose recommended by the National Asthma Education and Prevention
Program guidelines, which are published by the National Heart, Lung, and Blood Institute, as
compared with a lower dose which is commonly used in practice. We hypothesize that the lower
dose will be no worse than the higher dose as determined primarily by duration of
hospitalization.