Oral Propranolol for Reducing Pediatric Dental Patients Anxiety

• Status: Completed
• Trial end date: 2020-02-15
• Target enrollment: 0
• Participant gender: All

Summary

Evaluating anxiety, heart rate and behavior during dental extractions after oral dose of either Propranolol, Midazolam or a combination of both in uncooperative pediatric patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Damascus University
• Treatments: Midazolam; Propranolol

Criteria

Inclusion Criteria:

• High to extreme fear of tooth or molar anesthesia and removal (Frankl: Definitely negative).

• Scoring more than 19 points on MCDAS(f).

• Healthy pediatric patients (ASA I) aging 8-10 years.

• Indication for primary tooth or molar extraction.

• Fasting if indicated (severe gag reflex).

• Airway assessment (Mallampati and tonsillar hypertrophy).

Exclusion Criteria:

• Asthma or any other obstructive pulmonary disease.

• Cardiac failure.

• Cardiac arrhythmia.

• Renal failure.

• Diabetes.

• Current use of another ß-adrenoreceptor antagonist.

• Current use of anxiolytic or antidepressant medication.

• Currently in psychotherapy for dental anxiety.

• Systolic blood pressure <100 mmHg.

• Diastolic blood pressure <60 mmHg.

• Active Upper respiratory infection.