Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterior Approach.

• Status: Completed
• Trial end date: 2019-11-20
• Target enrollment: 0
• Participant gender: All

Summary

Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions . When unrelieved or poorly controlled, it is associated with medical complications, poor patient satisfaction and increased risk of developing chronic pain. Dexketoprofen is a new NSAID treating acute postoperative pain and when it combined with tramadol may have a better effect. The purpose of this study is to evaluate the analgesic effect of the oral use of the combination of dexketoprofen/tramadole on the reduction of postoperative pain after total hip arthroplasty with minimal invasive anterior approach (AMIS).

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: KAT General Hospital
• Treatments: Acetaminophen; Dexketoprofen trometamol; Levobupivacaine; Ropivacaine; Tramadol

Criteria

Inclusion Criteria:

• unilateral total hip arthroplasty with a direct anterior minimal invasive technique

• ASA score I or II

• signed written informed consent form

• 3 days hospitalization

• 45-80 years old

• primary Total hip arthroplasty

Exclusion Criteria:

• allergy to any given drugs

• contraindications for spinal anesthesia

• active bleeding

• renal failure ( gfr< 90ml/h)

• hepatic failure ( abnormal sgot,sgpt,γgt)

• heart failure

• history of gastrointestinal bleeding