Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J)
Status:
Completed
Trial end date:
2017-02-28
Target enrollment:
Participant gender:
Summary
The study will compare the outcomes of treating bone and joint infections with 6 weeks of
intravenous antibiotics with 6 weeks of oral antibiotic treatment. The trial is of antibiotic
"strategy" rather than of individual antibiotics. The study will be open label, but the
primary outcome will be proven failure of infection treatment, determined by pre-established
objective criteria for treatment failure. The null hypothesis tested is that there will be no
difference in treatment failure rates.