Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery

• Status: Unknown status
• Trial end date: 2018-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

Hypothesis: Postoperative pain will be equivalent in patients receiving preemptive oral acetaminophen as compared to patients receiving preemptive intravenous acetaminophen following minimally invasive benign gynecologic surgery.

Primary outcome:

• Difference in postoperative pain comparing preemptive use of PO versus IV acetaminophen

o Mean Visual analog Scale (VAS) scores will be compared between the intervention group (PO acetaminophen) and the control group (IV acetaminophen).

Secondary outcomes:

• Difference in postoperative analgesic use between groups

o Narcotics, NSAIDs

• Difference in postoperative N/V between groups

o Patient rated measure - none, mild, moderate, severe

• Cost comparison between drugs

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Scripps Health
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• Patients 18 years of age or older scheduled to undergo robotic-assisted laparoscopic hysterectomy for benign conditions.

Exclusion Criteria:

• Known or suspected malignancy,

• Active liver/renal disease,

• Chronic alcohol use/alcoholism,

• Allergy to acetaminophen,

• Conversion to laparotomy,

• hx gastroparesis,

• Poorly controlled insulin dependent diabetes or gastric bypass surgery,

• Regular/recent (past 6 months) narcotic use,

• Inability to swallow pills.