Overview

Orelabrutinib and Sintilimab in Relapsed or Refractory Central Nervous System Lymphoma

Status:
Recruiting
Trial end date:
2026-12-31
Target enrollment:
Participant gender:
Summary
This phase Ib/II trial is evaluating the efficacy and side effect of orelabrutinib and sintilimab as possible treatments for relapsed or refractory central nervous system lymphoma.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborators:
First Affiliated Hospital of Zhejiang University
First People's Hospital of Hangzhou
Huizhou Municipal Central Hospital
Jinhua Central Hospital
Jinhua People's Hospital
Second Affiliated Hospital of Wenzhou Medical University
Sir Run Run Shaw Hospital
Wenzhou Central Hospital
Yinzhou Hospital Affiliated to Medical School of Ningbo University
Zhejiang Provincial People's Hospital
Zhejiang Provincial Tongde Hospital