Overview

Organ Donation and Hydrocortisone Treatment

Status:
Terminated
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Brain death patients who are selected for organ donation very often suffer from haemodynamic instability. To treat this, high amounts of vasoactive drugs(norepinephrine) may be needed to raise blood pressure. However,norepinephrine may have negative influence on several organs causing reduced blood flow ischemia. Our hypothesis is that hydrocortisone treatment may reduce the amount of vasoactive drugs needed to keep the blood pressure stable in patients selected for organ donation.
Phase:
N/A
Details
Lead Sponsor:
Kuopio University Hospital
Collaborator:
Tampere University Hospital
Treatments:
Cortisol succinate
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate