Oseltamivir Treatment for Children Less Than 24 Months of Age With Influenza
Status:
Completed
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to learn how to treat influenza in children less than 2 years of
age. Tamiflu®, the drug being studied, is approved for treatment of children 1 year of age
and older with influenza. Researchers want to learn more about the activity of Tamiflu® in
the body to determine a dose of that is safe, well-tolerated, and effective in young children
with influenza. Children less than 24 months of age with confirmed influenza will receive
Tamiflu® 2 times a day for 5 days. Older participants will be enrolled first and younger
children will be enrolled after the safety data is reviewed for older participants. Study
procedures include blood samples, swabs from inside the nose, and body and nervous system
evaluations. Participants may be involved in study related procedures for up to 37 days.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)