Osteoarthritis in Older Adults: Recovery of Mobility and Pain With a Topical Analgesic
Status:
Withdrawn
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Biofreeze® is a topical ointment that has menthol and alcamphor. Its analgesic effect lies in
the stimulation of A and C fibers by cold and nociceptive stimulation, respectively, which is
produced by menthol, apparently through the newly discovered receptor TRPM8 (Transient
Receptor Potential melastatin-8) The aim of this study is to investigate if BIOFREEZE ®
treatment (Performance Health Inc., Export, PA) improves symptoms associated with moderate
knee osteoarthritis, which would decrease the immobility and isolation in older adults.