Outcome Following Antidepressant Treatment on Possible Endo-Phenotypes for Major Depression

• Status: Completed
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether outcome following antidepressant treatment can be used as a tool to evaluate endo-phenotypes for depression.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Copenhagen
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Offsprings or siblings of patients with major depression

• Born in Denmark with European parents and grandparents

• For women; not pregnant or breastfeeding

• Written informed consent

Exclusion Criteria:

• Somatically illness or other handicaps which make participation in the study impossible

• Daily intake of drugs interfering with corticosteroids or escitalopram

• Hypersensitivity to escitalopram, dexamethasone or human corticotropin-releasing hormone

• Former medical or psychological treatment for diseases in the affective or schizophrenic spectrum

• Ongoing addiction of alcohol or psychoactive drugs