Outcome of Combined Tramadol and Paracetamol Versus Pentazocine as Labour Analgesia Among Parturients

• Status: Not yet recruiting
• Trial end date: 2023-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

Labour is a very painful experience and epidural analgesia is considered the gold standard for pain relief in labour. Epidural scarcity, cost and shortage of skilled personnel to administer it is a limitation to it's usage in developing countries. Parenteral opioid analgesics such as pethidine and pentazocine are effective labour analgesia commonly used in developing countries but are limited by their side effects. This limitation in their use call for the need for alternative analgesic with similar or superior analgesic effect but with minimal side effects.The study is aimed at evaluating the efficacy and safety of combined tramadol and paracetamol in reducing labour pain among parturients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal Medical Centre, Yenagoa
• Treatments: Pentazocine

Criteria

Inclusion Criteria:

• All pregnant women who presented in spontaneous labour at term, carrying Singleton Live Fetus in Active Phase of Labour with Cervical dilatation of 4-6cm who gave consent to participate in the study

Exclusion Criteria:

• Women with severe medical conditions such as diabetes mellitus, severe pre-eclampsia, cardiac, liver and renal disease

• Preterm Labour

• Intrauterine Fetal Death

• Fetal presentation other than cephalic

• Patients with previous caeserean section

• History of hypersensitivity to paracetamol, tramadol and pentazocine

• Complications such as antepartum haemarrhage, polyhydramnious, premature rupture of membrane

• Use of any kind of analgesia before recruitment

• Multiple gestation

• All other delivery except spontaneous vertex delivery Labour that was induced or augmented