Outcome of Three Controlled Ovarian Hyperstimulation Protocols in Poor Responding Infertility Patients

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

There are different controlled ovarian hyperstimulation protocols utilized in infertility patients. In this study, our aim is to specifically compare three protocols in poor responding infertility patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Istanbul University
• Treatments: Chorionic Gonadotropin; Letrozole; Menotropins

Criteria

Inclusion Criteria:

• Patients will be considered eligible if they are poor ovarian responders according to the Bologna criteria (Ferraretti et al., 2011).

• Two out of three of the following criteria are essential in order to classify a patient as poor ovarian responder:

• advanced maternal age (≥40 years) or any other risk factor for poor ovarian response;

• a poor ovarian response (≤3 oocytes with a conventional stimulation protocol); or

• an abnormal ovarian reserve test (antral follicle count, <7 follicles or anti-Mullerian hormone, <1.1 ng/ml).