Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery

• Status: Not yet recruiting
• Trial end date: 2025-10-10
• Target enrollment: 0
• Participant gender: All

Summary

This will be an open, prospective, parallel-group, randomized controlled trial. Patients scheduled for complex anorectal surgery under general anesthesia will be enrolled, and the perioperative analgesia mode led by anesthesiologists will be established. Compared with the perioperative analgesia mode led by surgeons, the efficacy and safety of analgesia, quality of life and satisfaction of patients will be evaluated. This study is aimed at the feasibility and efficiacy of anesthesiologist-led treatment mode in the management of moderate and severe pain in patients after complex anorectal surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China-Japan Friendship Hospital

Criteria

Inclusion Criteria:

1. American Society of Anesthesia (ASA) grading I-III

2. ≥18 years old

3. Patients scheduled for complex anorectal surgery under general anesthesia, e.g., mixed hemorrhoidectomy/sclerosing agent injection/ligation, radical anal fistula resection, peri-anal abscess incision and drainage

Exclusion Criteria:

1. Informed consent not obtained

2. Allergic to general anesthetics, hydromorphone, non-steroidal anti-inflammatory drugs and other related ingredients

3. Opioid abuse or pathological pain that requires long-term analgesic treatment

4. History of severe asthma attack and acute phase of asthma

5. Moderate or above ventilatory function or diffusion dysfunction

6. Liver dysfunction reached Child B grade; Renal insufficiency reached chronic kidney disease (CKD) stage IV

7. Gastric retention and paralytic ileus

8. Pregnant and lactating patients