Over Active Bladder Patients Having Sling Surgery

• Status: Completed
• Trial end date: 2010-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether treatment with anti-muscarinic medications following sub-urethral sling procedures improves overall subjective and objective outcomes in women with mixed incontinence with primary stress symptoms.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cleveland Clinic Florida
• Collaborator: Astellas Pharma US, Inc.
• Treatments: Solifenacin Succinate; Tolterodine Tartrate

Criteria

Inclusion Criteria:

• Age >/= 18

• Patient is appropriate for sub-urethral sling procedure

• Mixed urinary incontinence

• No antimuscarinic therapy for previous 30 days

Exclusion Criteria:

• Uncontrolled narrow angle glaucoma

• Acute cystitis

• Unevaluated hematuria

• Currently using anti-muscarinic therapy

• Unable to complete pre-operative urodynamics

• Contraindication to anti-cholinergic therapy

• Unable or unwilling to complete diaries or quality of life questionaire

• Significant (exteriorized) Pelvic Organ Prolapse