Overview

Oxaliplatin and Capecitabine on Top of Sorafenib Versus Sorafenib Alone in Advanced Hepatocellular Carcinoma Patients

Status:
Withdrawn
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
Primary Objective: - To evaluate the efficacy of SECOX regimen by adding oxaliplatin plus capecitabine to sorafenib versus sorafenib alone as palliative treatment for unresectable HCC patients to prolong overall survival (OS) for advanced HCC patients. Secondary Objective: - To compare the efficacy of SECOX regimen with Sorafenib alone for progression free survival (PFS) - To compare the efficacy of SECOX regimen with Sorafenib alone for response rate (RR) - To assess the overall safety profile of SECOX regimen in comparison of Sorafenib alone
Phase:
Phase 3
Details
Lead Sponsor:
Sanofi
Treatments:
Capecitabine
Niacinamide
Oxaliplatin
Sorafenib