Oxidative Stress Related to 2 Different Oxygen Concentrations During General Anesthesia. Clinical Trial.
Status:
Unknown status
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Clinical trial controlled randomized of parallels groups. The study is designed to look for
differences in the oxidative stress level among healthy patients receiving 2 different oxygen
concentrations: 30% and 60% during general anesthesia. Once the patient has been informed,
the affirmative agreement has been obtained and inclusion and exclusion criteria verified the
patients are randomized to 30% or 60% oxygen concentration. In the operating room while
placing the intravenous line, a sample blood is obtained. General anesthesia is induced and
maintained with sevoflurane. After Anesthesia induction the anesthesia machine is fixed in
order to provide the oxygen concentration according to the randomization. One hour later a
second venous sample is obtained. Samples are stored in cold conditions until their analysis
in the laboratories of the biology faculty - Barcelona University.
Phase:
Phase 4
Details
Lead Sponsor:
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau