This randomized phase III trial studies how well oxybutynin chloride works in managing hot
flashes in patients who are not candidates for, or not interested in hormone replacement
therapy. Previous studies have shown that oxybutynin is effective in managing hot flashes,
however doses used in prior studies have resulted in side effects. This trial is evaluating
lower doses of oxybutynin with the goal of determining if they are efficacious with less side
effects.
ADAM-VTE