Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic Surgery
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
Inadequate control of acute postoperative pain (DAPO) brings deleterious consequences for the
patient, including significant cardiovascular and respiratory complications. Apart from the
human suffering that is undeniable pain. Schemes oral analgesia with opioids for the
treatment of DAPO, have shown to be as or more effective than intravenous or epidural
regimes, and less expensive. Comparing the effectiveness of 10 to 20 mgs of oxycodone
sustained release for 12 hours before surgery, into two groups of 20 patients (O-10, O-20)
undergoing orthopedic surgery, in a scheme involving multimodal ketoprofen, dipyrone
metoclopramide and dexamethasone. Values were recorded visual analog scale (VAS)for pain at
rest and effort, requirement for rescue intravenous morphine and incidence of side effects to
the entry and exit of the PACU (T0, TE) and at 6 and 18 hours postoperatively (T6, T18),and
patient satisfaction.