Oxytocin, Carbetocin and Misopristol for Treatment of Postpartum Hemorrhage: A Multicentric Randomized Trial
Status:
Unknown status
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
Postpartum hemorrhage (PPH) is the leading cause of maternal death worldwide, with an
estimated mortality of 140 000 per year. Uterine atony is one of the most important causes of
PPH. The traditional treatment of which is the use of uterotonic agents. Oxytocin is the most
conventional drug which was proved effective. However, it has the shortcomings of short half
life and the necessity of intravenous administration. Misopristol, and more recently
Carbetocin were introduced for treatment of atonic PPP not responding to Oxytocin.
Aim of the study is to evaluate the effectiveness of Carbetocin, Misopristol, and Oxytocin
for treatment of atonic PPH.