Oxytocin Dosing at Planned Cesarean Section and Anemia

• Status: Withdrawn
• Trial end date: 2020-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

Patient's with planned cesarean sections will be randomized to receive either standard 20 mU in 1L as a bolus following delivery of the placenta or 20 mu in 1L following delivery of the placenta plus an additional 20 mU in 1L over 8 hours.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Milton S. Hershey Medical Center
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Planned cesarean sections for singletons at or greater than 37 weeks gestational age

• Primary or repeat cesarean section will be included

Exclusion Criteria:

• Multiple fetal pregnancies

• Hematologic disorders

• Fetal anomalies

• Pre-eclampsia. These patients are at increased risk of fluid overload and so fluid status may be affected by receiving a second bag of fluid containing oxytocin in the postpartum period.

• Known contraindication to oxytocin

• Hypersensitivity to oxytocin

• Patients who have labored and then proceed with cesarean section for any reason. Patients who have labored have had either intrinsic or extrinsic exposure to oxytocin. These patients may have decreased sensitivity to oxytocin.