Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections

• Status: Unknown status
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Objective is to proof non-inferiority of intramyometrial and intravenous oxytocin application compared to intravenous carbetocin for prevention of postpartum hemorrhage in planned, uncomplicated cesarean deliveries.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Zurich
• Treatments: Carbetocin; Oxytocin

Criteria

Inclusion Criteria:

• elective cesarean section

• present informed consent

• completed 36 weeks of gestation

Exclusion Criteria:

• need for intubation (carbetocin is only licensed for epidural or spinal anesthesia)

• multiple fetus pregnancy

• known coagulopathy

• Placenta praevia

• morbidly adherent placenta

• placental abruption

• thrombocyte dysfunction

• HELLP-syndrome

• preeclampsia

• history of uterine atony