PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis (Volunteer - BioD and Safety Study)

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to assess the safety, biodistribution and dosimetry of the novel atherosclerotic imaging PET radiotracer, Cu[64]-25%-CANF-Comb.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Washington University School of Medicine

Criteria

Inclusion Criteria:

• Healthy volunteers (4 men and 4 women)

• No evidence of cardiovascular disease and not under care of a physician for any active medical condition

• Health status confirmed by physical exam and ECG

• Signed informed consent

Exclusion Criteria:

• Pregnancy or lactation

• Inability to lie still for up to 60 min with arms above head for PET-CT imaging

• Unwilling to comply with study procedures and unavailable for the duration of the study.

• Inability to provide written informed consent.