PET Synaptogenesis After Psilocybin In DEpression Recovery
Status:
Not yet recruiting
Trial end date:
2025-07-01
Target enrollment:
Participant gender:
Summary
Participants with depression will be given a single dose of psilocybin and supportive
psychotherapy before, during, and after drug administration. Participants will undergo
positron emission tomography (PET) imaging before and one week after psilocybin using a
marker of synaptic density. This design allows us to assess the relationship between
neurotrophic, and antidepressant effects produced by psilocybin.