Overview

PF-04995274 and Emotional Processing in Un-medicated Depression

Status:
Unknown status
Trial end date:
2020-04-30
Target enrollment:
Participant gender:
Summary
This study will test whether seven days administration of a serotonin receptor subtype 4 (5HT4) agonist called PF-04995274 has positive effects on emotional processing and neural activity in unmedicated depressed patients compared to placebo. The study will also include a group of patients randomised to seven days administration of citalopram (20 mg), which is a standard treatment for depression.
Phase:
Phase 1
Details
Lead Sponsor:
University of Oxford
Collaborators:
Medical Research Council
Pfizer
Treatments:
Citalopram
Dexetimide