Overview

PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years

Status:
Not yet recruiting

Trial end date:
2030-06-01

Target enrollment:

Participant gender:

Summary

To assess whether PFO closure plus antiplatelet therapy is superior to antiplatelet therapy alone and whether oral anticoagulant therapy is superior to antiplatelet therapy to prevent stroke recurrence in patients aged 60 to 80 years with a PFO with large shunt (> 20 microbubbles) or a PFO associated with an ASA (> 10 mm), and an otherwise unexplained ischemic stroke.

Phase:

Phase 3

Details

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborators:

Abbott
Centre Hospitalier St Anne
Gore
Ministry of Health, France
Occlutech International AB

Treatments:

Anticoagulants
Factor Xa Inhibitors