PK PD of the Enantiomers of Tramadol and O-desmethyltramadol in Elderly and Young Subjects
Status:
Completed
Trial end date:
2007-02-01
Target enrollment:
Participant gender:
Summary
This study evaluates the pharmacokinetics and pharmacodynamics of the enantiomers of tramadol
and O-desmethyltramadol (ODM) in generally healthy young and elderly adults. Using a
randomised, double-blind, crossover design, participants were administered a single 200mg
tramadol extended-release tablet and placebo.