PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Two cohorts of patients will be enrolled: Cohort A will consist of patients who are current
smokers, and Cohort B will consist of patients who are current nonsmokers. There will be 24
patients enrolled in each cohort. Nonsmokers are patients who have not consumed tobacco or
nicotine-containing products for 1 year before the start of the study. Patients classified as
current smokers must have smoked a minimum of 10 cigarettes per day for up to 1 year.
Patients who have smoked 1-9 cigarettes per day for up to 1 year, or more than 10 cigarettes
per day for less than 1 year will not be eligible for this study.