POLlinosis and Exhaled Breath Temperature

• Status: Unknown status
• Trial end date: 2013-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether exhaled breath temperature, a surrogate marker of airway inflammation, rises during the pollen season in sensitized subjects with allergic rhinoconjucnctivitis with or without mild asthma. Sublingual Immunotherapy with respective allergens suppresses the seasonal increase of EBT. During the second year (2013) of the trial all patients will be treated with 5 grass allergen extract: carry over differences between the active and placebo arms from the previous year (2012) will be looked for.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Prof. Todor Popov

Criteria

Inclusion Criteria:

• 60 randomized patients from either sex

• age range 5-55 years

• included patients should have a proven grass pollen sensitization

Exclusion Criteria:

• age under or above the stated

• lack of any other concomitant allergen sensitivities that may blur the clinical course of the natural exacerbation due to pollen