PPI for Prevention of Post-sphincterotomy Bleeding

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Endoscopic biliary sphincterotomy is a common and important procedure for biliary access and therapy during endoscopic retrograde cholangiopancreatography (ERCP). Bleeding is one of the important complications related to sphincterotomy. This study determines the role of proton pump inhibitor (PPI) in preventing post-sphincterotomy bleeding in patients undergoing ERCP and sphincterotomy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Hong Kong
• Treatments: Esomeprazole; Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• Consecutive patients undergoing ERCP who will require sphincterotomy

Exclusion Criteria:

• Previous sphincterotomy/papillotomy

• Previous Polya gastrectomy

• Patients on maintenance PPI

• Pregnant and lactating women

• Age <18 years

• Previous liver transplant

• unable to consent for study