PROTOCOL 3: Role of the Renal Nerves in the Increase in EGP in Response to Glucosuria
Status:
Completed
Trial end date:
2019-05-15
Target enrollment:
Participant gender:
Summary
Purpose/Objectives: Examining the effect of SGLT2 inhibition on EGP and plasma glucose
concentration in diabetic and non-diabetic subjects after kidney transplantation (i.e. renal
denervation) or in subjects after renal sympathectomy (63) can add insight about the possible
role of a neural arc which mediates the changes in plasma glucagon and/or insulin
concentration in response to glucosuria.
Phase:
Phase 4
Details
Lead Sponsor:
The University of Texas Health Science Center at San Antonio
Collaborators:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institutes of Health (NIH)