Overview PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) Status: Recruiting Trial end date: 2023-12-01 Target enrollment: Participant gender: Summary This is a pilot study, phase III, multi-centre, double blind, randomized controlled trial of patients with traumatic brain injury (TBI). Phase: Phase 3 Details Lead Sponsor: Sunnybrook Health Sciences CentreCollaborators: Canadian Institutes of Health Research (CIHR)Sunnybrook Research InstituteTreatments: AnticoagulantsDalteparinHeparin, Low-Molecular-WeightTinzaparin