Overview

PRP vs AD-SVF in Addition to Marrow Stimulation for Knee Chondral Lesion

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2026-05-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to learn if PRP and adipose-derived stem cells (AD-SVF) enhance healing after knee microfracture for chondral lesions. It will also learn about the safety of the procedure. The main questions it aims to answer are: Do PRP and AD-SVF get better results than PRP alone in patients undergoing arthroscopic microfracture for knee monocompartmental cartilage injuries? What medical problems do participants have when taking drug ABC? Researchers will compare PRP + AD-SVF to PRP alone to see if PRP + AD-SVF work better to treat knee cartilage injuries. Participants will: Undergo knee microfracture and biologics injections at the end of the arthroscopic procedure (PRP+AD-SVF vs PRP). Visit the clinic for checkups and tests at baseline and at 3, 6, 12 months post-treatment, and then annually.
Phase:
PHASE4
Details
Lead Sponsor:
Universit degli Studi dell'Aquila
Collaborator:
Arthrex GmbH