PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
Status:
Not yet recruiting
Trial end date:
2024-11-01
Target enrollment:
Participant gender:
Summary
The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized
controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of
200 mg oral micronized progesterone twice daily or placebo. The aims of this study are to
assess the feasibility, safety and preliminary efficacy of micronized progesterone for the
prevention of return to methamphetamine use. A secondary aim is to assess participant's
salivary levels of allopregnanolone with methamphetamine cravings. This study has the
potential to provide effective interventions to prevent methamphetamine use among postpartum
women.