PSLT Compared to Prostaglandin Analogue Eye Drops

• Status: Recruiting
• Trial end date: 2022-12-20
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare the efficacy of PSLT and the topical use of prostaglandin-like hypotensive eye drops in the treatment of ocular hypertensive or glaucomatous patients in decreasing intraocular pressure and measuring changes in functional, structural and biomechanical parameters evaluated by computerized perimetry and optical coherence tomography (OCT) related to pressure change resulting from treatments

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Federal University of Rio Grande do Sul
• Treatments: Ophthalmic Solutions

Criteria

Inclusion Criteria:

• Diagnosis of ocular hypertension (IOP ≥ 24 mmHg in both eyes) or diagnosis of open-angle glaucoma (POAG) in both eyes

• Proper visualization of angle structures and 360 degree open angles in both eyes

• No previous intraocular surgery with the exception of phacoemulsification with intraocular lens implantation

• No use of systemic medications known to increase IOP

Exclusion Criteria:

• Patients using more than two glaucoma medications

• Evidence of any other eye disease that could affect IOP measurement

• Diagnosis of other types of glaucoma

• Patient with mean deviation (MD) less than -12 decibels (dB) on visual perimetry (severe disease)

• Patients with unilateral glaucoma