PTH-related protein, or ''PTHrP'', is a hormone which was discovered in 1987. As its name
implies, it is closely related to another hormone discovered in the 1920's named parathyroid
hormone or ''PTH''. PTH has been shown to be effective in treating osteoporosis in both
animals and humans. PTHrP has been shown to be effective in treating osteoporosis in
laboratory animals, and there are strong scientific reasons to think that it may be effective
in humans as well. However, no human trials with PTHrP in the treatment of osteoporosis have
been performed. The studies in this trial are focussed on determining whether PTHrP can
indeed increase bone mass in postmenopausal women with osteoporosis, when administered daily
by subcutaneous injection for three months.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Treatments:
Hormones Parathyroid Hormone Parathyroid Hormone-Related Protein