Pain Control in Colorectal Surgery: Liposomal Bupivacaine Block Versus Intravenous Lidociane
Status:
Completed
Trial end date:
2021-07-20
Target enrollment:
Participant gender:
Summary
To compare the analgesic impact of intravenous perioperative lidocaine infusion with
preoperative liposomal bupivacaine TAP block in colorectal surgery. This is to be integrated
into the standard ERAS protocol currently utilized at Carolinas Medical Center. Primary
endpoints will be postoperative pain as measured by verbal rate scale (VRS), postoperative
morphine equivalents utilized per day, and over 30 days. Secondary endpoints will include
date of ambulation, return of bowel function (first flatus), tolerance of goal diet,
incidence of post-operative nausea and vomiting during hospital stay, length of stay
(hospital and PACU), post-operative morbidity (Clavien-Dindo, related to both anesthesia and
surgery), cost of hospitalization (operative, PACU, postoperative stay, and total) and
quality of life on follow up.