Pain Perception During Vulvar Biopsy

• Status: Terminated
• Trial end date: 2019-03-12
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to compare pain control during vulvar biopsy following either (1) application of EMLA (a eutectic mixture of local anesthetics lidocaine 2.5% and prilocaine 2.5%) cream or (2) injection of 1% lidocaine. We hypothesize that lidocaine will provide better biopsy analgesia, but the benefit will be offset by the pain of lidocaine injection compared to EMLA application, thus there will not be a significant difference in highest pain scores between the two groups.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Duke University
• Treatments: EMLA; Lidocaine

Criteria

Inclusion Criteria:

• Females above age 18 presenting to Duke Gynecology Oncology clinic for vulvar biopsy

• Able to provide informed consent in English and agree to the risks of the study

Exclusion Criteria:

• Not able to provide informed consent

• Vulvar biopsy on a hair bearing surface