Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain

• Status: Recruiting
• Trial end date: 2024-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain.

The study will be conducted in National Cancer Institute and all the participants will be enrolled from female patients scheduled for modified radical mastectomy under general anesthesia in National Cancer Institute, Cairo University.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Cancer Institute, Egypt
• Treatments: Duloxetine Hydrochloride; Magnesium Sulfate

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) physical I-II

• Scheduled for MRM

• Under general anesthesia.

Exclusion Criteria:

• Liver or kidney disease

• Patient with previous chronic pain on opioids

• Patients on antidepressants and antipsychotics.

• Allergies to study drugs