Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults

• Status: Completed
• Trial end date: 2019-12-23
• Target enrollment: 0
• Participant gender: All

Summary

This study is to investigate the effect of CBD on acute pain in healthy volunteers in a well-established acute pain model.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Basel, Switzerland
• Treatments: Epidiolex; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Healthy adults

• BMI between 18.5 until 25 kg/m2

• Able to understand the study and the NRS scale

• Able to give informed consent

Exclusion Criteria:

• Regular consumption of cannabinoids or other drugs / substances

• Regular intake of medications potentially interfering with pain sensation (analgesics, antihistamines, calcium and potassium channel blockers, serotonin / noradrenaline reuptake inhibitors, corticosteroids)

• Neuropathy

• Chronic pain

• Neuromuscular disease

• Psychiatric disease

• Known or suspected kidney or liver disease

• Pregnancy/ Lactation

• Allergy / hypersensitivity to cannabidiol