Pain Therapy After Elective Cardiac Surgery

• Status: Completed
• Trial end date: 2012-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine generation of a target controlled infusion model for the patient controlled analgesia with the strong analgesic, hydromorphone, after planned open heart surgery, during which the strong analgesic, sufentanil, was used.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Erlangen-Nürnberg Medical School
• Collaborator: German Federal Ministry of Education and Research
• Treatments: Dsuvia; Hydromorphone; Sufentanil

Criteria

Inclusion Criteria:

• Written informed consent,

• Ability to understand the nature of patient-controlled analgesia and other study-specific procedures,

• Elective cardiac surgery with thoracotomy and subsequent stay in the intensive care unit

Exclusion Criteria:

• Use of MAO inhibitors in the last 14 days,

• Chronic alcoholism or drug addiction in medical history,

• Severe obstructive or restrictive pulmonal disorders in medical history,

• Severe hepatic and renal disorders in medical history,

• Hypothyroidism, pancreatitis in medical history,

• ASA IV,

• Pregnant or nursing females