Overview

Palbociclib Plus Letrozole in Hormone Receptor Positive Residual Disease After Neoadjuvant Chemotherapy

Status:
Recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
PROMETEO II is a single-arm window of opportunity trial to evaluate biologic and anti-proliferative effects of palbociclib and letrozole in HR+/HER2-negative operable breast cancer (BC) patients with residual disease after neoadjuvant chemotherapy (NAC) and help to identify biomarkers for better patient selection.
Phase:
Early Phase 1
Details
Lead Sponsor:
SOLTI Breast Cancer Research Group
Collaborator:
Pfizer
Treatments:
Hormones
Letrozole
Palbociclib